| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8480771 | Seminars in Cell & Developmental Biology | 2014 | 9 Pages |
Abstract
This review focuses on studies performed on knock-out and knock-in Lmna mouse models, which have led to decipher some of the lamin A/C functions in striated muscles and to the first preclinical trials of pharmaceutical therapies.
Keywords
BNPMTOCL-CMDLGMDEDMDANFLAPEHTLBRLINCACEmTORMEFMAPKAngiotensin-converting enzymeengineered heart tissueknock-inEmery–Dreifuss muscular dystrophyLimb-girdle muscular dystrophyretinoblastomaUbiquitin proteasome systematrial natriuretic factorNupmicrotubule organizing centermouse embryonic fibroblastsknock-outwild-typemammalian target of rapamycinLamin A/Cnuclear envelopemitogen-activated protein kinasebrain natriuretic peptideLamin B receptorUPS
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Feriel Azibani, Antoine Muchir, Nicolas Vignier, Gisèle Bonne, Anne T. Bertrand,