| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8480803 | Seminars in Cell & Developmental Biology | 2014 | 8 Pages |
Abstract
- The axon initial segment (AIS) has a key role in the maintenance of neuronal polarity.
- The AIS is a large assembly of membrane proteins bound to an ankyrin G based scaffold.
- The AIS forms a surface diffusion barrier and an intracellular traffic filter.
- The cytoskeleton arrangement suggests molecular mechanisms for the barrier and filter.
Keywords
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Cell Biology
Authors
Christophe Leterrier, Bénédicte Dargent,