Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8485455 | Vaccine | 2018 | 9 Pages |
Abstract
Early T-cell responses which we have previously observed at the duodenal mucosa 18â¯days following oral vaccination with Ty21a could not be detected at a median of 1.5â¯years. Peripheral responses were observed at this time. Immunoglobulin responses observed shortly after vaccination were not associated with cellular immune responses at 1.5â¯years, suggesting that the persistence of cellular immunity is not associated with the strength of the initial humoral response to vaccination.
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Authors
Shaun H. Pennington, Daniela M. Ferreira, Jesús Reiné, Tonney S. Nyirenda, Ameeka L. Thompson, Carole A. Hancock, Angela D. Wright, Stephen B. Gordon, Melita A. Gordon,