Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8486264 | Vaccine | 2018 | 9 Pages |
Abstract
Simian adenoviral vectored vaccines encoding genetic segments that are conserved between all major HCV genotypes contain multiple T-cell epitopes and are highly immunogenic in pre-clinical models. These studies pave the way for the assessment of multi-genotypic HCV T-cell vaccines in humans.
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Authors
Annette von Delft, Timothy A. Donnison, José Lourenço, Claire Hutchings, Caitlin E. Mullarkey, Anthony Brown, Oliver G. Pybus, Paul Klenerman, Senthil Chinnakannan, Eleanor Barnes,