Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8486552 | Vaccine | 2017 | 8 Pages |
Abstract
All vaccination regimes elicited serum and mucosal antibody responses to alpha toxin and to secreted proteins of both nvNetB+ and a very virulent NetB positive (vvNetB+) strain (p < 0.0001 to p < 0.05). In some vaccinated groups, there was milder intestinal pathology upon disease challenge. 55% of birds vaccinated orally at days 2, 12 with nvNetB+ adjuvanted with CT did not develop any lesions of NE by 6 days post challenge, compared to a 100% incidence of NE lesions in the unvaccinated disease challenged group.
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Authors
Neha Mishra, Joan A. Smyth,