| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8486725 | Vaccine | 2012 | 6 Pages |
Abstract
⺠Early vaccines miss a pentameric gH complex important for viral epithelial entry. ⺠We restored expression of the complex in AD169 virus for evaluation in animals. ⺠Virus with restored complex can induce. ⺠10-fold higher neutralizing antibodies. ⺠Peak titers post vaccination within 2-4-fold of those in HCMV positive subjects.
Keywords
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Immunology and Microbiology
Immunology
Authors
Tong-Ming Fu, Dai Wang, Daniel C. Freed, Aimin Tang, Fengsheng Li, Xi He, Suzanne Cole, Sheri Dubey, Adam C. Finnefrock, Jan ter Meulen, John W. Shiver, Danilo R. Casimiro,