Prevalence of prolonged and chronic poliovirus excretion among persons with primary immune deficiency disorders in Sri Lanka

► Patients with primary immune deficiency (PID) may acquire Sabin like polioviruses when the oral polio vaccine is used+. ► In patients with PID these viruses may be excreted for a longer period, and acquire mutations leading to neurovirulence. ► Patients with X linked agammaglobulinemia (XLA) and common variable immune deficiency (CVID) may excrete the virus for longer periods, posing a threat to the community. ► Patients with XLA and CVID should be regularly screened for poliovirus excretion to manage this risk.