Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8486763 | Vaccine | 2012 | 7 Pages |
Abstract
⺠Macrophages infected with recombinant (r) BCG become apoptotic. ⺠Apoptotic vesicles contain antigenic cargo. ⺠Engulfment of apoptotic vesicles by dendritic cells results in crosspriming. ⺠Crosspriming leads to better T cell stimulation. ⺠Superior protection by rBCG involves crosspriming.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Maura Farinacci, Stephan Weber, Stefan H.E. Kaufmann,