| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8497893 | Developmental & Comparative Immunology | 2016 | 8 Pages |
Abstract
Gastrointestinal infection can provoke substantial disturbance at both a local as well as at a systemic level and may evolve into a chronic disease state. Our growing knowledge of gut-pathogen interactions has been based to a large extent on the use of genetically tractable model hosts such as the fruit fly Drosophila melanogaster. In this review we will summarise the growing literature and critically address the advantages and disadvantages of using this model to extrapolate results from studying pathogen virulence and intestinal responses to humans.
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Authors
Rupal Mistry, Ilias Kounatidis, Petros Ligoxygakis,