| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8500239 | International Journal for Parasitology | 2013 | 13 Pages |
Abstract
⺠A worm-derived product, ES-62, protects against allergic airway inflammation induced by ovalbumin in mice. ⺠Protection is associated with resetting of the Th1/Th2 balance and correlates with suppression of Th17 responses. ⺠The study provides important information on the mechanism of action of a parasitic helminth-derived immunomodulator. ⺠The immunomodulator offers novel and safe therapeutic potential in the treatment of allergic diseases.
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Authors
Justyna Rzepecka, Ivonne Siebeke, Jennifer C. Coltherd, Dorothy E. Kean, Christina N. Steiger, Lamyaa Al-Riyami, Charles McSharry, Margaret M. Harnett, William Harnett,