Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8500240 | International Journal for Parasitology | 2013 | 7 Pages |
Abstract
⺠Declining prevalence of parasites in developed countries correlates with increased incidence of inflammatory disorders. ⺠Hookworms condition the immune system to prevent autoimmune and allergic inflammatory disorders. ⺠Administration of hookworm excretory/secretory proteins mimics the immunomodulatory properties of live worm infection. ⺠Hookworm excretory/secretory proteins modulate inflammatory bowel diseases in mice. ⺠Hookworm molecules have progressed through phase II clinical trials as therapeutics for human diseases.
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Authors
Severine Navarro, Ivana Ferreira, Alex Loukas,