Article ID Journal Published Year Pages File Type
8500240 International Journal for Parasitology 2013 7 Pages PDF
Abstract
► Declining prevalence of parasites in developed countries correlates with increased incidence of inflammatory disorders. ► Hookworms condition the immune system to prevent autoimmune and allergic inflammatory disorders. ► Administration of hookworm excretory/secretory proteins mimics the immunomodulatory properties of live worm infection. ► Hookworm excretory/secretory proteins modulate inflammatory bowel diseases in mice. ► Hookworm molecules have progressed through phase II clinical trials as therapeutics for human diseases.
Related Topics
Life Sciences Immunology and Microbiology Parasitology
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