| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8500273 | International Journal for Parasitology | 2011 | 8 Pages |
Abstract
⺠Mice lacking P2X7 receptor function (P2X7R knockout) lost more weight than C57Bl/6J mice (partial P2X7R function) and BALB/c mice (full P2X7R function) after infection with Toxoplasma. ⺠Absence of the P2X7R did not affect IFN-γ, IL-12, IL-1β or TNF production. ⺠P2X7R knockout mice had prolonged production of nitric oxide after infection with Toxoplasma. ⺠P2X7R knockout mice had delayed production of IL-10 after infection with Toxoplasma.
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Authors
Catherine M. Miller, Alana M. Zakrzewski, Rowan J. Ikin, Nicola R. Boulter, Marilyn Katrib, Michael P. Lees, Stephen J. Fuller, James S. Wiley, Nicholas C. Smith,