Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8500283 | International Journal for Parasitology | 2011 | 7 Pages |
Abstract
⺠Cryptosporidium parvum infection induces ICAM-1 expression in host epithelial cells. ⺠Downregulation of microRNA-122 (miR-221) occurs in C. parvum-infected cells. ⺠miR-221 targets ICAM-1 and mediates C. parvum-induced ICAM-1 expression. ⺠Expression of ICAM-1 on infected epithelial cells facilitates Jurkat cell adherence.
Keywords
Related Topics
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Immunology and Microbiology
Parasitology
Authors
Ai-Yu Gong, Guoku Hu, Rui Zhou, Jun Liu, Yaoyu Feng, Garrett A. Soukup, Xian-Ming Chen,