Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8500284 | International Journal for Parasitology | 2011 | 12 Pages |
Abstract
⺠Trypanosoma cruzi poly(ADP-ribose) polymerase (PARP) translocates to the nucleus in response to DNA damage. ⺠PAR metabolism is involved in at least two DNA strand break signalling pathways. ⺠PARP is connected with different cell death programs. ⺠Different DNA damaging agents induce distinct patterns of PARylated proteins.
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Authors
Salomé C. Vilchez Larrea, Guillermo D. Alonso, Mariana Schlesinger, Héctor N. Torres, Mirtha M. Flawiá, Silvia H. Fernández Villamil,