| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8500289 | International Journal for Parasitology | 2011 | 7 Pages |
Abstract
⺠2-Desoxoparaherquamide (2-DOPH) has direct and marked effects on motility in cut Caenorhabditis elegans worms. ⺠2-DOPH is a nicotinic acetylcholine receptor (nAChR) antagonist in C. elegans. ⺠Monepantel and derquantel may not suffer from a negative interaction if used together. ⺠Classical nAChR antagonists lack affinity for the monepantel-sensitive receptor. ⺠Permeability properties of C. elegans may limit its use in anthelmintic screening.
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Authors
Elizabeth Ruiz-Lancheros, Charles Viau, Tita N. Walter, Abdel Francis, Timothy G. Geary,