Akabane, Aino and Schmallenberg virus - where do we stand and what do we know about the role of domestic ruminant hosts and Culicoides vectors in virus transmission and overwintering?

The mechanism by which these Simbu viruses cross-pass yearly periods of very low vector abundance in temperate climate zones remains undefined. Yearly wind-borne reintroductions of infected midges from tropical endemic regions with year-round vector activity have been proposed, just as overwintering in long-lived adult midges. Experimental and field data however indicate that a role of vertical virus transmission in the ruminant host currently cannot be excluded as an overwintering mechanism. More studies on Culicoides biology and specific groups of transplacentally infected newborn ruminants without gross malformations are needed to shed light on this matter.