| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8516112 | Medical Hypotheses | 2018 | 24 Pages |
Abstract
Putting all the pieces of experimental evidence together, we hypothesize that tramadol might alleviate AD pathological hallmarks at least in cellular level through decreasing activity of PI3K-AKT and ERK and also mTOR signaling pathways respectively and results in autophagy activation as well as tau-dephosphorylation.
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Authors
Leila Pourtalebi Jahromi, Zahra Sasanipour, Amir Azadi,