| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8516381 | Neuropharmacology | 2018 | 8 Pages |
Abstract
Our results indicate that the α5 nAChR subunit plays a role in the effects of varenicline on nicotine reward in mice. Moreover, the mediation of α5 nAChRs, but not β2 nAChRs are probably needed for aversive properties of varenicline at high dose. Varenicline was also shown to reduce several nicotine withdrawal signs.
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Behavioral Neuroscience
Authors
Deniz Bagdas, Yasmin Alkhlaif, Asti Jackson, F. Ivy Carroll, Joseph W. Ditre, M. Imad Damaj,