Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real?

Article ID	Journal	Published Year	Pages	File Type
8517635	Neuropharmacology	2017	55 Pages	PDF

Keywords

SAR Inhibitory cystine knot POPG ICK DOPG Cryo-EM GUV PoPC MSP VSD GMT dHPC nuclear magnetic resonance 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-l-serine 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine 1,2-dioleoyl-sn-glycero-3-phosphoglycerol 1,2-diheptanoyl-sn-glycero-3-phosphocholine POPs large unilamellar vesicle NMR Surface plasmon resonance SPR Voltage sensor domain SMA Pain Structure activity relationship Rational drug design Model membranes Giant unilamellar vesicle phosphatidylinositol phosphatidylcholine phosphatidylethanolamine Phosphatidylserine LUV SUV Cryo-electron microscopy Nav POPE membrane scaffold protein Sodium Channel voltage-gated sodium channel Voltage-gated potassium channel Small unilamellar vesicle

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Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real?

Authors

Akello J. Agwa, Sónia T. Henriques, Christina I. Schroeder,