Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8517934 | Phytomedicine | 2018 | 30 Pages |
Abstract
Some secondary metabolites from plants reveal radioprotective features against cellular damage caused by irradiation. These results warrant further analysis to develop phytochemicals as radioprotectors for clinical use.
Keywords
Bcl-2MDACATGSTEGCGCBMNGPXsirtuin1PI-3KGSHEGF-RiNOSPGE2ERK2ERK1AP-1GSRDSBsPTKphosphatidyl inositol-3-kinasePhosphorylated c-Jun N-terminal kinasemitogen-activated protein kinase 3mitogen-activated protein kinase kinase 1/2Tumor growth factor βTGF-βSCESirt1CAPEMAPKMEK1/2Mitogen activated protein kinasesNFκBp-JnkROSSSBsHydrogen peroxidesuperoxide anionSide effectsloss of heterozygosityepigallocatechin gallateinterleukinBaxionizing radiationSister chromatid exchangetumor necrosis factor αRadioprotectionRadiotherapyHydroxyl radicalsWorld Health OrganizationSODCancerNSCLCinducible nitric oxide synthaseSuperoxide dismutaseTNF-αnuclear factor kappa BPhytochemicalTRAILB-cell lymphoma 2LOHLow-density lipoproteinLDLTNF-related apoptosis-inducing ligandmalondialdehydeNitric oxideH2O2Bcl-2-associated X proteinProtein tyrosine kinaseactivator protein-1mitogen-activated protein kinasemitogen-activated protein kinase 1Prostaglandin E2non-small cell lung carcinomachloramphenicol acetyltransferaseWHOMAP kinaseGlutathioneglutathione-S-transferaseglutathione reductaseglutathione peroxidaseReactive oxygen speciesEpidermal growth factor receptor
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Authors
Nicolas Fischer, Ean-Jeong Seo, Thomas Efferth,