A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine

Article ID	Journal	Published Year	Pages	File Type
8518263	Phytomedicine	2018	55 Pages	PDF

Keywords

Mrp2 MDAS RLMs DDAs Benzoylaconine Benzoylmesaconine DMEs P-gp HDI Bcrp tmax ETs MRT BMA GST CyP UGT LD50 SNPs BHA Cmax AUC HLMs BAC P-glycoprotein t1/2 Aconitum alkaloids Drug-metabolizing enzymes Aconitine total body clearance herb-drug interactions Herb-drug interaction maximum plasma concentration efflux transporters Toxicology Cytochrome P450 apparent permeability coefficient Pharmacokinetics area under the plasma concentration–time curve Mesaconitine median lethal dose Mean residence time Rat liver microsomes Human Liver Microsomes efflux ratio elimination half-life Hypaconitine Papp multidrug resistance-associated protein 2 breast cancer resistance protein Personalized medicine Single nucleotide polymorphisms glutathione S-transferase

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Clinical Biochemistry

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A systematic review of pharmacokinetic studies on herbal drug Fuzi: Implications for Fuzi as personalized medicine

Authors

Jin-jun Wu, Zhen-zhen Guo, Yuan-feng Zhu, Zhi-jian Huang, Xia Gong, Yu-huan Li, Wen-jie Son, Xiao-yan Li, Yan-mei Lou, Li-jun Zhu, Lin-lin Lu, Zhong-qiu Liu, Liang Liu,