Anti-inflammatory activity of Khayandirobilide A from Khaya senegalensis via NF-ÎºB, AP-1 and p38 MAPK/Nrf2/HO-1 signaling pathways in lipopolysaccharide-stimulated RAW 264.7 and BV-2 cells

Article ID	Journal	Published Year	Pages	File Type
8518482	Phytomedicine	2018	34 Pages	PDF

Keywords

NF-κB Nrf2/HO-1 TLR4 Heme oxygenase-1 IKK AP-1 PGE2 iNOS qRT-PCR COX-2 HO-1 Nrf2 MYD88 PBS LPS IL-6 keap1 IκB kinase MAPKs ROS enzyme linked immunosorbent assay KLA interleukin-6 ELISA tumor necrosis factor-α inducible nitric oxide synthase Cyclooxygenase-2 Anti-inflammatory myeloid differentiation factor 88 nuclear factor E2-related factor 2 TNF-α nuclear factor-κB Limonoids lipopolysaccharide Phosphate-buffered saline Nitric oxide quantitative real-time polymerase chain reaction Kelch-like ECH-associated protein 1 Prostaglandin E2 mitogen-activated protein kinases Reactive oxygen species Toll-like receptor 4

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Clinical Biochemistry

Anti-inflammatory activity of Khayandirobilide A from Khaya senegalensis via NF-ÎºB, AP-1 and p38 MAPK/Nrf2/HO-1 signaling pathways in lipopolysaccharide-stimulated RAW 264.7 and BV-2 cells

Authors

Miao-Miao Zhou, Wen-Yan Zhang, Rui-Jun Li, Chao Guo, Shan-Shan Wei, Xiao-Meng Tian, Jun Luo, Ling-Yi Kong,