| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8523410 | Antiviral Research | 2018 | 33 Pages |
Abstract
In conclusion, the antiviral effects of NAPs in DHBV infected ducks and patients with chronic HBV infection were weak or absent in woodchuck and mouse models despite similar liver accumulation of NAPs in all these species, suggesting that the mechanisms of SVP assembly and or secretion present in rodent models differs from that in DHBV and chronic HBV infections.
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Authors
Katrin Schöneweis, Neil Motter, Pia L. Roppert, Mengji Lu, Baoju Wang, Ingo Roehl, Dieter Glebe, Dongliang Yang, John D. Morrey, Michael Roggendorf, Andrew Vaillant,