| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8524595 | Biomedicine & Pharmacotherapy | 2018 | 7 Pages |
Abstract
In conclusion, the present review demonstrates that upregulated Rho kinase activity involves in the pathogenesis of all aspects of metabolic syndrome. Taken together, these results implicate the therapeutic potential of the Rho-kinase pathway as an important new target in medicine.
Keywords
PTPMLCPMLCSREBPNADPHFFACypAPAI-1PKGMCP-1AMPKPPAReNOSIRSNCEPGLUTHDL-CPKBPKCSAHVSMPI3KIDFRASMCNOX-1JISUCP-1ASCVDGTPNCEP-ATP IIIoxLDLOxidized LDLNADPH oxidase 1ROSAktDyslipidemiaFree fatty acidendothelial nitric oxideNational Cholesterol Education ProgramAtherosclerotic cardiovascular diseasetriacylglycerolUncoupling protein-1Glucose transporterSubarachnoid hemorrhageIntravenousmyosin light chainWorld Health OrganizationRat aortic smooth muscle cellsEndothelial cellsAgeMetabolic syndromebody mass indexBMIVascular smooth muscletumor necrosis factorTNF-αHypertensionlow density lipoproteinLDLMETSInsulin resistancePlasminogen activator inhibitor-1Nitric oxidenicotinamide adenine dinucleotide phosphatesterol regulatory element binding proteinmonocyte chemoattractant protein-1protein kinase Bprotein kinase B (PKB)protein kinase GProtein kinase CWHOGuanosine triphosphateReactive oxygen speciesinsulin receptorPeroxisome proliferator activated receptorRock
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Authors
Vajiheh Jahani, Atefeh Kavousi, Soghra Mehri, Gholamreza Karimi,