| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8525906 | Biomedicine & Pharmacotherapy | 2018 | 8 Pages |
Abstract
A multitude of clinical studies showed the elevation of YKL-40 in subjects with different kinds of tumors. It is predicted that an inherent correlation exists between survivals of cancer patients with total YKL-40 serum levels, making this factor as a potential novel biomarker. However, the crucial role of YKL-40 in the dynamics of cancers, especially angiogenesis, has not yet been completely addressed. In this review, we highlighted the various facets of YKL-40 and its importance in cancer biology as a bio-shuttle in gene therapy.
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Authors
Ayda Pouyafar, Milad Zadi Heydarabad, Soltanali Mahboob, Ahad Mokhtarzadeh, Reza Rahbarghazi,