Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8525925 | Biomedicine & Pharmacotherapy | 2018 | 7 Pages |
Abstract
Turmeric, an important spice all around the world, is obtained from the rhizomes of Curcuma longa, a member of the Zingiberaceae family. It has been used in the prevention and treatment of many diseases since ancient times. Curcumin is the principal polyphenol isolated from turmeric. Several evidences have shown the anti-inflammatory, antioxidant, anti-tumor, anti-angiogenesis, and anti-metastatic activities of curcumin. In this review, relevant articles on the effect of curcumin on endometriosis and possible molecular mechanisms are discussed.
Keywords
B cell lymphoma-2FGFBcl-2TACHUVECCCl4MDAIGF-1Nrf2-Keap1IFN-γAP-1MCP-1HIF-1αPDGFIκ-BIL-8MVDELAM-1VCAM-1HGFHER-2TIMP-2ICAM-1COX-2NF-κBMMPEGFIL-6PBMCTGF-βGPXGnRHROSEndometriosisinsulin-like growth factor-1interferon-γInterleukin-8interleukin-6Baxtransforming growth factor-βMicrovessel densitytumor necrosis factor-αImmune systemTurmericHuman umbilical vein endothelial cellsperipheral blood mononuclear cellscyclooxigenase-2Total antioxidant capacityhypoxia-inducible factor-1αepidermal growth factorHepatocyte growth factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet derived growth factorfibroblast growth factorTNF-αnuclear factor-κBmatrix metalloproteinasemalonaldehydemembrane type 1 matrix metalloproteinaseinhibitor of kappa Bintracellular adhesion molecule-1vascular cell adhesion molecule-1endothelial leukocyte adhesion molecule-1gonadotropin releasing hormonehuman papilloma virusesHPVBcl-2-associated X proteinmonocyte chemoattractant protein-1activator protein-1PolyphenolCarbon tetrachlorideCurcuminglutathione peroxidaseReactive oxygen speciesHuman epidermal growth factor receptor-2
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Authors
Tahereh Arablou, Roya Kolahdouz-Mohammadi,