Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8525931 | Biomedicine & Pharmacotherapy | 2018 | 5 Pages |
Abstract
In conclusion, SIRT1 regulates apoptosis, inflammation and oxidative stress resulting in improving DR. This review focuses on the role of SIRT1 in DR.
Keywords
ICAMNAMPTglial fibrillary acidicGLP-1RPENICDMnSODET-1PPARαAGEsMMP-9Sir2GFAPRECSTGFβ1HDACsT helperPRMT1TNFNF-κBSirt1AMPKECMHIFsNAD+endothelin-1retinal pigment epithelialDiabetesTransforming growth factor β1Oxidative stressRetinopathyperipheral blood mononuclear cellsretinal endothelial cellsmanganese superoxide dismutaseVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)tumor necrosis factorFoxOFibronectinextra cellular matrixAdvanced glycation end productsintracellular adhesion moleculeNitric oxidenicotinamide adenine dinucleotidenicotinamide phosphoribosyl transferase
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Authors
Hedyieh Karbasforooshan, Gholamreza Karimi,