Pharmacotherapeutic potential of phytochemicals: Implications in cancer chemoprevention and future perspectives

Article ID	Journal	Published Year	Pages	File Type
8526006	Biomedicine & Pharmacotherapy	2018	23 Pages	PDF

Keywords

Bcl-xL HO-1 mTOR COX-2 Bcl-2 ERK RAS SRC GAE iNOS RAF EGFR FADD AP-1 PARP NQO1 TGFβ1 TSG PGES IKKβ TNF related apoptosis inducing ligand GPx-1 Fas associated death domain nuclear factor erythroid 2 p45-related factor 2 Phosphorylated c-Jun N-terminal kinase UGT NF-κB Nrf2 PI3K α-SMA GST DME Janus kinase keap1 c-Myc EpRE MAPKs Mitogen activated protein kinases ROS uridine diphosphate glucuronosyltransferase STAT AIF α-smooth muscle actin Bax tumour necrosis factor α Apoptosis retinoblastoma Sarcoma SOD inducible nitric oxide synthase Cancer cell metabolism Superoxide dismutase cyclooxygenase 2 apoptosis inducing factor antioxidant response element electrophile response element Fas Ligand FasL Vascular endothelial growth factor Vascular Endothelial Growth Factor (VEGF)TNF-α nuclear factor-κB Bioavailability phosphatidylinositol-3-kinase rapidly accelerated fibrosarcoma Phytochemicals TRAIL B-cell lymphoma 2 Signal transducer and activator of transcription Redox modulation Gallic acid equivalent rutin equivalent mammalian target of rapamycin ARE heme oxygenase 1 Bcl-2 Associated X protein activator protein 1 Kelch-like ECH-associated protein 1 Prostaglandins poly ADP ribose polymerase Chemoprevention JAK Pten Tumour suppressor gene extracellular signal-regulated kinase glutathione-S-transferase glutathione peroxidase 1 Reactive oxygen species Epidermal growth factor receptor

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Pharmacotherapeutic potential of phytochemicals: Implications in cancer chemoprevention and future perspectives

Authors

Varinder Kaur, Manish Kumar, Ajay Kumar, Kamaldeep Kaur, Varinderpal Singh Dhillon, Satwinderjeet Kaur,