Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8526162 | Biomedicine & Pharmacotherapy | 2018 | 8 Pages |
Abstract
We demonstrated that PTER suppressed the growth, and invasion of HCC and was effective in regulating the levels of the MTA1/HDAC1/NuRD complex, promoting PTEN acetylation and apoptosis in HCC. Our findings suggest that the novel epigenetic nature of PTER anticancer activity opens up new avenues for primary chemoprevention, as well as anticancer and antimetastatic treatment.
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Authors
Yu-yuan Qian, Zhi-su Liu, Hua-jun Yan, Yu-feng Yuan, Anait S. Levenson, Kun Li,