Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8527102 | Chinese Journal of Natural Medicines | 2017 | 4 Pages |
Abstract
Two new phragmalin-type limonoids orthoesters, encandollens A and B (1 and 2), were isolated from the stem barks of Entandrophragma candollei collected in Ghana. The structures of these compounds were elucidated on the basis of HR-ESI-MS, 1H and 13C NMR, HSQC, HMBC, and ROESY data. Compound 1 was a rare C-15 enolic acyl phragmalin-type limonoid orthoester. Compounds 1 and 2 exhibited weak inhibitory effects on NO production in lipopolysaccharide (LPS)-induced RAW 264.7 cells.
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Authors
Olga QUASIE, Hui LI, Jun LUO, Ling-Yi KONG,