| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8527414 | Chinese Journal of Natural Medicines | 2017 | 4 Pages |
Abstract
The present study was designed to investigate the chemical constituents of the whole herb of Dichrocephala benthamii. A new megastigmane glucoside (compound 1), together with its four known analogues (compounds 2â5), was obtained. Their structures were elucidated on the basis of spectroscopic analyses (UV, IR, MS, and 1D and 2D NMR). The absolute configuration of compound 1 was assigned on the basis of CD method and chemical evidence. In addition, their cytotoxicity against human hepatoma cells (HepG-2) was evaluated by the MTT method. Compound 5 showed weak activity against HepG-2, while the other compounds did not show remarkable inhibitory effects.
Related Topics
Health Sciences
Medicine and Dentistry
Complementary and Alternative Medicine
Authors
Bo SONG, Jin-Guang SI, Meng YU, Xiao-Hui TIAN, Gang DING, Zhong-Mei ZOU,