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Involvement of mTOR, JNK and PI3K in the negative effect of ethanol and metformin on the human first-trimester extravillous trophoblast HTR-8/SVneo cell line

Article ID Journal Published Year Pages File Type
8528909 European Journal of Pharmacology 2018 30 Pages PDF
Abstract
We show that EtOH and METF have a detrimental effect in placentation-related processes of HTR-8/SVneo cells. Moreover, mTOR, JNK and PI3K appear to mediate some of these negative effects.
Keywords
PI3KJnkmTORTrophoblastsEthanolMetformin
Related Topics
Life Sciences Neuroscience Cellular and Molecular Neuroscience
Preview
Involvement of mTOR, JNK and PI3K in the negative effect of ethanol and metformin on the human first-trimester extravillous trophoblast HTR-8/SVneo cell line
Authors
Ana Correia-Branco, Elisa Keating, Fátima Martel,
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Journal
European Journal of Pharmacology
Journal: European Journal of Pharmacology
Related Categories
PI3K
Jnk
mTOR
Trophoblasts
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Metformin
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Neurology
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