| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8529003 | European Journal of Pharmacology | 2018 | 35 Pages |
Abstract
In conclusion, zebrafish and human K2P17.1 channels display similar structural and regulatory properties. Zebrafish may serve as an in vivo model to study neuronal K2P17.1 function but does not appear appropriate for cardiac electrophysiology studies. Differences in pH sensitivity of zK2P17.1 currents need to be considered when zebrafish data are extrapolated to human physiology.
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Authors
Ingo Staudacher, Claudius Illg, Jakob Gierten, Sebastian Seehausen, Patrick A. Schweizer, Hugo A. Katus, Dierk Thomas,