| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8529335 | European Journal of Pharmacology | 2018 | 8 Pages |
Abstract
The antinociceptive effect of morphine partially depends by the N/OFQ-NOP system that participates in the development of morphine tolerance. In particular, NOP receptors are involved in morphine-induced astrocyte activation, and N/OFQ per se increases astrocyte density.
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Authors
Laura Micheli, Elena Lucarini, Francesca Corti, Roberto Ciccocioppo, Girolamo Calò, Anna Rizzi, Carla Ghelardini, Lorenzo Di Cesare Mannelli,