Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8529495 | European Journal of Pharmacology | 2018 | 26 Pages |
Abstract
Ligustilide exerted neuroprotective effects in mice after cerebral ischemia by regulating anti-inflammatory and anti-oxidant signaling pathways. Furthermore, klotho upregulation contributes to the neuroprotection of LIG against cerebral ischemic injury. These results indicated that ligustilide may be a promising therapeutic agent for the treatment of cerebral ischemia.
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Authors
Fang-Yi Long, Meng-Qi Shi, Hong-Jing Zhou, Dong-Ling Liu, Na Sang, Jun-Rong Du,