Article ID Journal Published Year Pages File Type
8529509 European Journal of Pharmacology 2018 19 Pages PDF
Abstract
In conclusion, our results allow suggesting that Ap4A-induced inhibitory effects in the rat heart are mediated by PKC, but not by NO/sGC/PKG-related signaling pathway. In addition, PDE stimulation may contribute to Ap4A-caused inhibition of the rat heart contractility.
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Life Sciences Neuroscience Cellular and Molecular Neuroscience
Preview
Negative inotropic effects of diadenosine tetraphosphate are mediated by protein kinase C and phosphodiesterases stimulation in the rat heart
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