| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8529553 | European Journal of Pharmacology | 2018 | 11 Pages |
Abstract
These data define therapeutically relevant exposures correlated with mechanism-based activity in GN, while toxicological evaluation suggests a large therapeutic index and provides evidence for achieving safe and effective exposure to a MIF isoform-directed therapeutic in nephritis-associated disease.
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Authors
Werner Höllriegl, Alexander Bauer, Bernhard Baumgartner, Barbara Dietrich, Patrice Douillard, Randolf J. Kerschbaumer, Gerald Höbarth, Jeffrey S. McKee, Alexander Schinagl, Frederick W.K. Tam, Michael Thiele, Alfred Weber, Martin Wolfsegger,