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Obeticholic acid raises LDL-cholesterol and reduces HDL-cholesterol in the Diet-Induced NASH (DIN) hamster model

Article ID Journal Published Year Pages File Type
8529822 European Journal of Pharmacology 2017 31 Pages PDF
Abstract
Compared to mouse and rat models, the DIN hamster replicates benefits and side effects of OCA as observed in humans, and should be useful for evaluating novel drugs targeting NASH.
Keywords
nonalcoholic steatohepatitisobeticholic acidLipoproteinHamstercholesterol
Related Topics
Life Sciences Neuroscience Cellular and Molecular Neuroscience
Preview
Obeticholic acid raises LDL-cholesterol and reduces HDL-cholesterol in the Diet-Induced NASH (DIN) hamster model
Authors
François Briand, Emmanuel Brousseau, Marjolaine Quinsat, Rémy Burcelin, Thierry Sulpice,
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Journal
European Journal of Pharmacology
Journal: European Journal of Pharmacology
Related Categories
nonalcoholic steatohepatitis
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