Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8531124 | International Immunopharmacology | 2018 | 7 Pages |
Abstract
Treg proportions are reduced in ischemic stroke patients and increased by treatment with high-dose PARP-1 inhibitor JPI-289. The PARP-1 inhibitor also had a possible anti-inflammatory effect on cytokine levels, and may ameliorate the outcome of ischemic stroke by up-regulating Tregs.
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Authors
Min-Young Noh, Won Moo Lee, Su-Jung Lee, Hyun Young Kim, Seung Hyun Kim, Young Seo Kim,