| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8531405 | International Immunopharmacology | 2018 | 10 Pages |
Abstract
Easy-understanding summary: A novel compound isolated from herbal medicine (DCK) suppressed the biological functions of dendritic cells (DC), including DC activation and DC-mediated Th1 and Th17 cell differentiation, which was associated with the NF-κB signaling pathway. This work suggested a potential therapeutic role of DCK in treating inflammatory skin diseases like psoriasis.103
Keywords
PAMPchemokine (CC motif) ligand40,6-diamidino-2-phenylindoleIMQT-helperCCLGM-CSFTGFTLRDCsDAPIOVAdCKERKCCRMFIAPCsAntigen presenting cellsSDS-PAGESodium dodecyl sulfate polyacrylamide gel electrophoresispathogen-associated molecular patternsOvalbuminImiquimodinterferonIFNinterleukintransforming growth factorDendritic cellsgranulocyte-macrophage colony-stimulating factormean fluorescence intensityPsoriasisextracellular signal-regulated kinaseToll-like receptors
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Authors
Qing Liu, Wei Yin, Ling Han, Jiaoyan Lv, Bingji Li, Yuli Lin, Qingsheng Mi, Rui He, Chuanjian Lu,