Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8531601 | International Immunopharmacology | 2018 | 7 Pages |
Abstract
Anti-TNF drugs disinhibit B cell production in IBD patients, but maintain the constant homeostasis of circulating B cells. The presence of individual variations may allow the activity of anti-TNF drugs to be monitored by studying B cell subgroups.
Keywords
IPCPerCP-Cy5.5PPBSPTPN2IFNγT-helperMBSHBSPBSAPCIBDFITCmAbsAPEallophycocyaninantigen-presenting cellinterferon-gammaCrohn's diseaseInflammatory bowel diseasePCsplasma cellsMemory B cellsphycoerythrinfluorescein isothiocyanatePhosphate-buffered salinegerminal centrebone marrowHematogonesMonoclonal antibodiesPlasmablastsUlcerative colitis
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Authors
Caterina Defendenti, Fabiola Atzeni, Sergio Malandrin, Sandro Ardizzone, Piero Luigi Almasio, Simone Saibeni, Cristina Bezzio, Simona Bollani, Raffaele Salerno, Paolo Declich, Zoe Sarno, Savino Bruno, Rossella Talotta, Piercarlo Sarzi-Puttini,