Combined treatment with Dendrobium candidum and black tea extract promotes osteoprotective activity in ovariectomized estrogen deficient rats and osteoclast formation

Both animal models and in vitro experiments suggested that the combination of Dendrobium candidum and black tea extract may effectively ameliorate the symptoms of osteoporosis. One partial mechanism of this combination might be the inhibition of osteoclast proliferation and the regulation of NFATC1/c-Fos expression.182