Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8535681 | Life Sciences | 2018 | 9 Pages |
Abstract
Hypothetical biochemical pathway illustrating the possible role of native HA and degraded HA in inflamed tissues.175
Keywords
Hsp-70Bcl-2iNOSPGE2IL-1βECMTLR-4A2ARIL-17TRAF6proteoglycansGAGsPGSCOL1A1PrPCol3a1Col2a1Aggrecan4-MU4-methylumbelliferoneACANBcl2 associated X proteinProstaglandin E-2Col10a1HYAL-1COL5A1TGF-βHASsCD44MmpsCTGFNF-kBβ-TCPkDaTGF-β1mRNANSAIDSMYD88IL-6ADAMTs-5ROSβ-tricalcium phosphateArthritisRheumatoid arthritisOsteoarthritisJoint inflammationLOXinterleukin-17interleukin-6Interleukin-1βBaxTransforming Growth Factor BetaTransforming growth factor beta-1tumor necrosis factor-αNonsteroidal anti-inflammatory drugsinducible nitric oxide synthasehyaluronan synthasesCytokinesHeat shock protein-70Connective tissue growth factorTNF-αnuclear factor kappa-light-chain-enhancer of activated B cellsSynovial fibroblastsB-cell lymphoma 2Extracellular matrixMetalloproteinasesLipoxygenase inhibitorNitric oxideHyaluronanHyaluronidasespolymerase chain reactionPCRmyeloid differentiation primary response gene 88platelet-rich plasmakilodaltonsGlycosaminoglycansReactive oxygen species
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Authors
Angela Avenoso, Angela D'Ascola, Michele Scuruchi, Giuseppe Mandraffino, Alberto Calatroni, Antonino Saitta, Salvatore Campo, Giuseppe M. Campo,