Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8537321 | Progress in Neuro-Psychopharmacology and Biological Psychiatry | 2018 | 7 Pages |
Abstract
Caloric restriction, and caloric restriction mimetics (e.g. resveratrol) are all capable of upregulating sirtuin isoforms implicated in stress response syndromes. Repurposing existing treatments and/or discovery of novel agents capable of modulating sirtuin physiology may represent genuinely novel approaches for trans-diagnostic domains affected in mood disorders and other brain-based illnesses.
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Authors
Asem Alageel, Julia Tomasi, Claudia Tersigni, Elisa Brietzke, Hannah Zuckerman, Mehala Subramaniapillai, Yena Lee, Michelle Iacobucci, Joshua D. Rosenblat, Rodrigo B. Mansur, Roger S. McIntyre,