| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8537755 | Pulmonary Pharmacology & Therapeutics | 2018 | 14 Pages |
Abstract
Activation and inhibition of RhoA-ROCK pathway by LPA and FSD modulated the homeostasis of Th17/Treg cells via regulating STAT3/STAT5 phosphorylation in hypoxic PAH. Thus, Apart from influence of pulmonary vascular remodeling, regulation of Th17/Treg homeostasis by RhoA-ROCK pathway play a key role in hypoxic PAH.
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Authors
Cheng Li, Ping-ping Liu, Dou-dou Tang, Rong Song, Yi-qing Zhang, Si Lei, Shang-jie Wu,