| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8538978 | Toxicology and Applied Pharmacology | 2018 | 35 Pages |
Abstract
A variety of therapeutically useful drugs degranulate MCs. This action may account for side effects such as the intrathecal granuloma resulting from spinally-delivered opioids. This degranulating effect may be useful in predicting potential intrathecal toxicity in the development of novel agents.
Keywords
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Eric Schmidt-Rondon, Zhenping Wang, Shelle A. Malkmus, Anna Di Nardo, Keith Hildebrand, Linda Page, Tony L. Yaksh,