Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8544819 | Chemico-Biological Interactions | 2018 | 41 Pages |
Abstract
The possible mechanism of protective effect of paeonol on epirubicin-induced cardiotoxicity.The repressed autophagy induced by epirubicin was involved in myocardial apoptosis and that paeonol, a potential myocardial protective drug, effectively ameliorated myocardial injury by reinforcing slight autophagy. This occurred through increased miR-1 expression to suppress the PI3K/AKT/mTOR and NF-κB signalling pathways.121
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Authors
Jing Wu, Chao Sun, Ruoyi Wang, Juan Li, Meng Zhou, Mi Yan, Xia Xue, Chuanxin Wang,