Article ID Journal Published Year Pages File Type
8544819 Chemico-Biological Interactions 2018 41 Pages PDF
Abstract
The possible mechanism of protective effect of paeonol on epirubicin-induced cardiotoxicity.The repressed autophagy induced by epirubicin was involved in myocardial apoptosis and that paeonol, a potential myocardial protective drug, effectively ameliorated myocardial injury by reinforcing slight autophagy. This occurred through increased miR-1 expression to suppress the PI3K/AKT/mTOR and NF-κB signalling pathways.121
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Life Sciences Environmental Science Health, Toxicology and Mutagenesis
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Cardioprotective effect of paeonol against epirubicin-induced heart injury via regulating miR-1 and PI3K/AKT pathway
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