Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8545698 | Environmental Toxicology and Pharmacology | 2018 | 9 Pages |
Abstract
In recent years, titanium dioxide (TiO2) nanoparticles (NPs) as metal oxide nanoparticles are widely used in industry, agriculture, personal care products, cosmetics, sun protection and toothpaste, electronics, foodstuffs and food packaging. This use of nano-TiO2 has been associated with environmental toxicity concerns. Therefore, the aim of this study was to evaluate the in vitro effect of different doses of TiO2 NPs (â¼30-40â¯nm) (0.01, 0.1, 0.5, 1, 10 and 50â¯mg/L) at 4oC for 3â¯h on the sperm cell kinematics as velocities of Rainbow trout (Oncorhynchus mykiss, Walbaum, 1792) sperm cells. Furthermore, oxidative stress markers (total glutathione (TGSH) and superoxide dismutase (SOD) were assessed in sperm cells after exposure to TiO2 NPs. According to the obtained results, there were statistically significant (Pâ¯<â¯0.05) decreasing in the velocities of sperm cells after 10â¯mg/L TiO2 NPs and an increase the activity of SOD (Pâ¯<â¯0.05) and TGSH levels were determined.
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Authors
Mustafa Erkan Ãzgür, Sevgi BalcıoÄlu, Ahmet Ulu, İmren Ãzcan, Fatih OkumuÅ, Süleyman Köytepe, Burhan AteÅ,