Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8549739 | International Journal of Hygiene and Environmental Health | 2018 | 8 Pages |
Abstract
This is the first study of clinically confirmed diagnoses of ASD that utilized repeated measurements of organophosphate metabolites during pregnancy to explore the associations between these pesticides and ASD risk in children. The association we observed among girls, as well as the lack of association in boys, need to be replicated in further studies with similar design and larger sample size. In light of the higher baseline risk for ASD in this cohort, generalizability to children lacking a first degree relative affected by ASD is unknown.
Keywords
DEDTPSCQDMPDEPADI-RDETPDMDTPDMTPOrganophosphate pesticidesAutism spectrum disorderAutism Diagnostic Observation ScheduleDiethyldithiophosphatediethylthiophosphatediethylphosphatedimethylthiophosphateDimethyldithiophosphatedimethylphosphatebody mass indexBMIPrenatal exposureAutism Diagnostic Interview-RevisedBiomarkersADOSProspective cohortSocial Communication Questionnaire
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Authors
Claire Philippat, Jacqueline Barkoski, Daniel J. Tancredi, Bill Elms, Dana Boyd Barr, Sally Ozonoff, Deborah H. Bennett, Irva Hertz-Picciotto,