Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro

Article ID	Journal	Published Year	Pages	File Type
8550743	Regulatory Toxicology and Pharmacology	2018	11 Pages	PDF

Keywords

HO-1 UGT1A1 NAPQI NQO1 Ginsenoside Rg1 GCL SFN GCLC CYP450 ALT Rg1 Hemeoxygenase-1 GSH Nrf2 GCLM CAT nuclear factor erythroid-2-related factor 2 N-acetyl-p-benzoquinoneimine Acetaminophen (APAP)UDP-glucuronosyltransferase 1A1 MDA NAD(P)H:quinine oxidoreductase 1 keap1 AST Acute liver injury alanine transaminase aspartate transaminase Oxidative stress SOD Sulforaphane Superoxide dismutase Cytochrome P450 lactate dehydrogenase LDH glutamate-cysteine ligase malondialdehyde ARE Catalase reduced glutathione glutamate-cysteine ligase modifier subunit glutamate-cysteine ligase catalytic subunit

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Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro

Authors

Chenqing Ning, Xiaoguang Gao, Changyuan Wang, Yulong Kong, Zhihao Liu, Huijun Sun, Pengyuan Sun, Xiaokui Huo, Xiaodong Ma, Qiang Meng, Kexin Liu,